KCNK16

Across TCGA patient cohorts, KCNK16 protein abundance is significantly associated with the RNA expression of many other genes, with 11,213 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNK16-associated genes across cancer lineages are TNFRSF10C, TRAPPC9, and FCGR2A. Each is linked with KCNK16 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNK16-to-partner and partner-to-KCNK16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNK16 versus TNFRSF10C in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK16→partner) and Y-score (partner→KCNK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNFRSF10C →	+0.845	+0.484	.002	.002	3	5
LUAD	TRAPPC9 →	-0.420	-0.500	.003	.005	3	5
HNSC	FCGR2A →	+0.821	+0.336	<.001	.001	3	5
PDAC	MCEMP1 →	+1.038	+0.408	<.001	.002	3	5
HNSC	TNFRSF12A →	+1.367	+0.432	<.001	<.001	3	5
HNSC	SPATA20P1 →	+1.235	+0.476	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,213 associations by consensus.

KCNK16 vs TNFRSF10C — UCEC

Explore this scatter interactively →