KCNK16

Across TCGA cell cohorts, KCNK16 RNA expression is significantly associated with the go_rna of many other GO terms, with 441 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KCNK16-associated GO terms across cancer lineages are Regulation of iron ion import across plasma membrane, Monocarboxylic acid transport, and Regulation of organelle assembly. Each is linked with KCNK16 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNK16-to-partner and partner-to-KCNK16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of iron ion import across plasma membrane grouped by KCNK16-low versus KCNK16-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK16→partner) and Y-score (partner→KCNK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of iron ion import across plasma membrane →	-0.099	-0.031	.003	.009	3	3
LUNG_SCLC	Monocarboxylic acid transport →	-0.043	-1.716	.001	.009	3	3
LUNG_SCLC	Regulation of organelle assembly →	+0.030	+1.609	.007	.001	2	4
LUNG_SCLC	Negative regulation of chromatin organization →	+0.108	+1.676	.001	.001	3	3
LUNG_SCLC	Cardiac left ventricle morphogenesis →	+0.224	+2.179	.002	.001	3	3
LUNG_SCLC	Negative regulation of MyD88-dependent toll-like receptor signaling pathway →	-0.921	-2.450	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 441 associations by consensus.

Regulation of iron ion import across plasma membrane by KCNK16 expression — BLOOD_Leukemia

Explore this box plot interactively →