Across TCGA patient cohorts, KCNK12 RNA expression is significantly associated with the RNA expression of many other genes, with 16,987 significant associations in total. LAML shows the largest number of these associations.

The most reproducible KCNK12-associated genes across cancer lineages are MSH2-OT1, CPT1C, and UNC13A. Each is linked with KCNK12 in more than 24 cancer types. Because this analysis shows association rather than direction, both KCNK12-to-partner and partner-to-KCNK12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK12→partner) and Y-score (partner→KCNK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	MSH2-OT1 →	+1.249	+1.063	<.001	<.001	3	25
SCLC	CPT1C →	+1.575	+0.965	<.001	.003	3	22
SCLC	UNC13A →	+1.525	+1.014	<.001	<.001	3	22
GBM	NTNG2 →	+0.830	+0.494	<.001	<.001	3	21
THYM	CARMIL2 →	+1.287	+0.190	<.001	<.001	3	21
ACC	CHST8 →	+1.976	+0.697	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,987 associations by consensus.

Exploration

KCNK12 survival (RNA) · tumor vs normal (RNA) · all KCNK12 data types