KCNK1

Across TCGA cell cohorts, KCNK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,064 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KCNK1-associated GO terms across cancer lineages are Autophagosome membrane docking, Positive regulation of iron ion transport, and Positive regulation of iron ion transmembrane transport. Each is linked with KCNK1 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCNK1-to-partner and partner-to-KCNK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome membrane docking grouped by KCNK1-low versus KCNK1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK1→partner) and Y-score (partner→KCNK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Autophagosome membrane docking →	+0.152	+2.273	<.001	.002	3	11
OVARY	Positive regulation of iron ion transport →	+1.869	+2.390	<.001	<.001	3	11
OVARY	Positive regulation of iron ion transmembrane transport →	+1.869	+2.390	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Regulation of resting membrane potential →	+1.367	+1.964	<.001	<.001	3	10
STOMACH	Cell-cell adhesion mediated by cadherin →	+0.185	+2.036	.001	<.001	3	10
BONE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.089	+2.062	.006	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,064 associations by consensus.

Autophagosome membrane docking by KCNK1 expression — STOMACH

Explore this box plot interactively →