KCNJ18

Across TCGA patient cohorts, KCNJ18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,573 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible KCNJ18-associated GO terms across cancer lineages are Organelle fusion, Regulation of binding, and Membrane fusion. Each is linked with KCNJ18 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCNJ18-to-partner and partner-to-KCNJ18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle fusion grouped by KCNJ18-low versus KCNJ18-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ18→partner) and Y-score (partner→KCNJ18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Organelle fusion →	+0.024	+0.059	<.001	<.001	3	9
KIRC	Regulation of binding →	+0.021	+0.060	<.001	<.001	3	8
KIRC	Membrane fusion →	+0.029	+0.075	<.001	<.001	3	8
KICH	Obsolete positive regulation of mitochondrion organization →	+0.019	+0.027	<.001	<.001	3	8
KIRC	Response to reactive oxygen species →	+0.019	+0.057	<.001	<.001	3	8
KIRC	ATP synthesis coupled electron transport →	+0.026	+0.048	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,573 associations by consensus.

Organelle fusion by KCNJ18 expression — KIRC

Explore this box plot interactively →