KCNIP1

Across TCGA patient cohorts, KCNIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,832 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNIP1-associated genes across cancer lineages are EXOSC9, CEP128, and PSMD9. Each is linked with KCNIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNIP1-to-partner and partner-to-KCNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EXOSC9 grouped by KCNIP1-low versus KCNIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNIP1→partner) and Y-score (partner→KCNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EXOSC9 →	+0.511	+2.606	<.001	<.001	3	3
SKCM	CEP128 →	+0.393	+2.254	.009	.006	3	2
UCEC	PSMD9 →	+0.392	+2.186	<.001	.001	3	2
SKCM	MTRF1L →	+0.502	+3.347	.002	.004	3	2
SKCM	RASSF8 →	+0.813	+2.913	.006	.001	3	2
SKCM	ATP1B2 →	-1.920	-3.993	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,832 associations by consensus.

EXOSC9 by KCNIP1 expression — UCEC

Explore this box plot interactively →