KCNIP1

Across TCGA patient cohorts, KCNIP1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNIP1-associated genes across cancer lineages are PDCD4, Shc_pY317, and ASNS. Each is linked with KCNIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNIP1-to-partner and partner-to-KCNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by KCNIP1-low versus KCNIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNIP1→partner) and Y-score (partner→KCNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.460	-1.502	.007	.030	3	2
UCEC	Shc_pY317 →	-0.180	-2.459	.001	.018	3	2
UCEC	ASNS →	+0.398	+2.222	.002	.010	3	2
UCEC	Chk2_pT68 →	-0.166	-2.674	.015	.005	3	2
UCEC	14-3-3_beta →	-0.110	-2.558	.002	.010	3	1
UCEC	eEF2 →	+0.345	+1.874	.008	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

PDCD4 by KCNIP1 expression — UCEC

Explore this box plot interactively →