Across TCGA patient cohorts, KCNH7 protein abundance is significantly associated with the RNA expression of many other genes, with 650 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNH7-associated genes across cancer lineages are ZNF345, HSCB, and EEF1A2. Each is linked with KCNH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNH7-to-partner and partner-to-KCNH7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH7→partner) and Y-score (partner→KCNH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF345 →	-1.090	-0.651	.006	.007	3	2
COAD	HSCB →	+0.411	+0.355	.007	.008	3	1
COAD	EEF1A2 →	-0.354	-0.583	.008	<.001	3	1
COAD	SRPX2 →	-1.722	-0.575	<.001	.002	3	1
COAD	AP3B2 →	-0.151	-0.517	.006	<.001	3	1
COAD	IL7 →	+0.847	+0.490	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 650 associations by consensus.

Exploration

KCNH7 survival (RNA) · tumor vs normal (RNA) · all KCNH7 data types