Across TCGA patient cohorts, KCNH7 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNH7-associated genes across cancer lineages are Stathmin, Mre11, and 4E-BP1. Each is linked with KCNH7 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNH7-to-partner and partner-to-KCNH7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH7→partner) and Y-score (partner→KCNH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Stathmin →	-0.099	-1.575	.023	.004	3	3
UCEC	Mre11 →	-0.054	-1.253	.023	.049	3	3
UCEC	4E-BP1 →	+0.158	+1.906	.035	.014	3	3
COAD	MIG-6 →	+0.120	+3.334	.003	.005	3	3
STAD	Heregulin →	-0.198	-2.984	.042	.034	3	2
STAD	RBM15 →	+0.482	+3.321	.020	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

KCNH7 survival (RNA) · tumor vs normal (RNA) · all KCNH7 data types