KCNG4

Across TCGA cell cohorts, KCNG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 281 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCNG4-associated GO terms across cancer lineages are DNA double-strand break attachment to nuclear envelope, Regulation of fibroblast migration, and Regulation of cell-substrate adhesion. Each is linked with KCNG4 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNG4-to-partner and partner-to-KCNG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA double-strand break attachment to nuclear envelope grouped by KCNG4-low versus KCNG4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG4→partner) and Y-score (partner→KCNG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA double-strand break attachment to nuclear envelope →	+0.120	+0.309	<.001	.002	3	3
SOFT_TISSUE	Regulation of fibroblast migration →	-0.060	-0.206	.001	.004	3	2
SOFT_TISSUE	Regulation of cell-substrate adhesion →	-0.044	-0.189	.003	.009	3	2
SOFT_TISSUE	tRNA decay →	+0.109	+0.234	<.001	.007	3	2
SOFT_TISSUE	Positive regulation of reactive oxygen species biosynthetic process →	-0.066	-0.205	<.001	.004	3	2
SOFT_TISSUE	Negative regulation of miRNA processing →	-0.107	-0.197	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 281 associations by consensus.

DNA double-strand break attachment to nuclear envelope by KCNG4 expression — SOFT_TISSUE

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