KCNG4

Across TCGA cell cohorts, KCNG4 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCNG4-associated genes across cancer lineages are OR6C2, SLURP1, and IL36A. Each is linked with KCNG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNG4-to-partner and partner-to-KCNG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C2 grouped by KCNG4-low versus KCNG4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNG4→partner) and Y-score (partner→KCNG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR6C2 →	+0.019	+5.369	<.001	.004	3	2
SOFT_TISSUE	SLURP1 →	+0.058	+5.369	<.001	.004	3	1
SOFT_TISSUE	IL36A →	+0.024	+4.930	.002	.008	3	1
SOFT_TISSUE	OR2M5 →	+0.019	+5.369	<.001	.004	3	1
SOFT_TISSUE	RPL10L →	+0.038	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR51I1 →	+0.648	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

OR6C2 by KCNG4 expression — SOFT_TISSUE

Explore this box plot interactively →