KCNE5

Across TCGA patient cohorts, KCNE5 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNE5-associated genes across cancer lineages are RNY3P12, RNU6-520P, and RNU2-64P. Each is linked with KCNE5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNE5-to-partner and partner-to-KCNE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY3P12 grouped by KCNE5-low versus KCNE5-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE5→partner) and Y-score (partner→KCNE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNY3P12 →	+0.664	+5.421	<.001	.005	3	1
READ	RNU6-520P →	+0.487	+5.219	<.001	.006	3	1
READ	RNU2-64P →	+0.513	+5.421	<.001	.005	3	1
READ	LINC00265-2P →	+0.083	+5.653	<.001	.003	3	1
READ	ABCD1P4 →	+0.107	+5.219	<.001	.006	3	1
READ	RPL32P19 →	+0.223	+5.653	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNY3P12 by KCNE5 expression — READ

Explore this box plot interactively →