Q-omics provides the consensus-scored RNY3P12 profile across patient tissues and cancer cell-line models. RNY3P12 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, RNY3P12 is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, RNY3P12 RNA expression shows 6,986 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UCEC, BRCA, and GBM as cancer lineages where RNY3P12 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNY3P12 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNY3P12 survival associations across molecular data types. RNY3P12 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNY3P12 RNA expression–survival associations across cancer types. High RNY3P12 expression shows unfavorable associations in UCEC, ACC, READ, CESC, KICH and HNSC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UCEC as the clearest survival context for RNY3P12 RNA expression.
This table summarizes RNY3P12 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNY3P12. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNY3P12 shows higher tumor expression in BRCA and KIRC. The BRCA box plot shows higher RNY3P12 RNA expression in tumor versus normal tissue (log2 FC = +0.199, t-test p = .023).
This table shows molecular features associated with RNY3P12 in patient tissues and cancer cell lines. In patient samples, RNY3P12 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
