KCNA3

Across TCGA cell cohorts, KCNA3 mutation is significantly associated with the RNA expression of many other genes, with 531 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNA3-associated genes across cancer lineages are OR10G7, BANF2, and FERD3L. Each is linked with KCNA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA3-to-partner and partner-to-KCNA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G7 grouped by KCNA3-low versus KCNA3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA3→partner) and Y-score (partner→KCNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR10G7 →	+0.010	+5.357	<.001	.001	3	1
LUNG_SCLC	BANF2 →	+0.206	+3.817	.006	.004	3	1
LUNG_SCLC	FERD3L →	+1.346	+4.070	<.001	.003	3	1
LUNG_SCLC	PRAMEF10 →	+0.708	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF17 →	+0.008	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF15 →	+0.382	+3.817	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 531 associations by consensus.

OR10G7 by KCNA3 expression — CNS

Explore this box plot interactively →