KCNA10

Across TCGA patient cohorts, KCNA10 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNA10-associated genes across cancer lineages are Notch1, Cyclin-B1, and FASN. Each is linked with KCNA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNA10-to-partner and partner-to-KCNA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by KCNA10-low versus KCNA10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA10→partner) and Y-score (partner→KCNA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.198	+2.428	<.001	.001	3	3
UCEC	Cyclin-B1 →	+0.744	+2.201	<.001	<.001	3	3
UCEC	FASN →	+0.295	+1.584	.025	.034	3	2
UCEC	FoxM1 →	+0.189	+1.321	.029	.029	3	2
UCEC	JNK_pT183_Y185 →	-0.189	-2.188	<.001	<.001	3	2
UCEC	Ku80 →	+0.260	+1.887	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Notch1 by KCNA10 expression — UCEC

Explore this box plot interactively →