KCNA10

Across TCGA pan-cancer cohorts, KCNA10 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated KCNA10 data layer compared with 5 for mutation status.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher KCNA10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KCNA10 expression acts as an unfavorable survival marker, although some lineages such as SCLC and UCS show a favorable association.

CESC, UVM, and BLCA are the cancer types where KCNA10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Quartile	All	0.576	0.785	<.001	62	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
BLCA	DFS	Tertile	All	0.249	0.373	.012	36	view →
MESO	OS	Tertile	All	0.276	0.439	.007	32	view →
TGCT	DFS	Quartile	III,IV	0.340	1.000	.006	22	view →
SCLC	OS	Tertile	III,IV	0.861	0.468	.004	20	view →
UCS	DFS	Tertile	II,III,IV	0.516	0.162	.015	16	view →
KIRC	DFS	Tertile	All	0.668	0.819	.004	12	view →
LUAD	DFS	Median	IV	0.666	0.978	.015	12	view →
GBM	OS	Tertile	All	0.204	0.432	.047	9	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	6	view →
ESCA	DFS	Tertile	All	0.407	0.247	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

KCNA10–CESC (DFS)

Open the CESC breakdown →