KCNA10

Across TCGA pan-cancer cohorts, KCNA10 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KCNA10’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where KCNA10 RNA is repressed in tumor relative to normal tissue. In most cancer types KCNA10 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and COAD are the cancer types where KCNA10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNA10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.329	<.001	8	view →
LUAD	All	All	−0.243	<.001	7	view →
COAD	All	All	+0.054	<.001	6	view →
HNSC	All	All	+0.046	.009	5	view →
STAD	Male	All	+0.054	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

KCNA10–LUSC

Open the LUSC breakdown →