KCNA10

Across TCGA cell cohorts, KCNA10 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNA10-associated genes across cancer lineages are STRA8, FGF21, and RAMP3. Each is linked with KCNA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA10-to-partner and partner-to-KCNA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STRA8 grouped by KCNA10-low versus KCNA10-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA10→partner) and Y-score (partner→KCNA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	STRA8 →	+0.431	+3.544	<.001	.009	3	2
BLOOD_Leukemia	FGF21 →	+0.264	+3.744	<.001	.003	3	2
SKIN	RAMP3 →	+0.680	+3.626	<.001	.006	3	1
SKIN	SLC17A1 →	+0.006	+4.022	<.001	.006	3	1
SKIN	GPR26 →	+0.107	+3.510	<.001	.003	3	1
SKIN	CCR5 →	+0.022	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

STRA8 by KCNA10 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →