KBTBD8

Across TCGA patient cohorts, KBTBD8 mutation is significantly associated with the RNA expression of many other genes, with 5,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD8-associated genes across cancer lineages are VDAC1P9, RNU6-39P, and RN7SKP214. Each is linked with KBTBD8 in more than 2 cancer types. Because this analysis shows association rather than direction, both KBTBD8-to-partner and partner-to-KBTBD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VDAC1P9 grouped by KBTBD8-low versus KBTBD8-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD8→partner) and Y-score (partner→KBTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	VDAC1P9 →	+0.110	+5.219	<.001	.006	3	3
LUSC	RNU6-39P →	+0.438	+3.684	<.001	.009	3	3
UCEC	RN7SKP214 →	+0.141	+1.486	<.001	.001	3	3
UCEC	NCOA4P1 →	+0.042	+1.239	<.001	.009	3	3
LIHC	TMEM225 →	+0.154	+6.149	<.001	.002	3	2
READ	EIF4A1P12 →	+0.960	+5.039	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,742 associations by consensus.

VDAC1P9 by KBTBD8 expression — READ

Explore this box plot interactively →