KBTBD13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KBTBD13 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KBTBD13-associated genes across cancer lineages are TSPY25P, MIR551A, and MIR4667. Each is linked with KBTBD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD13-to-partner and partner-to-KBTBD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY25P grouped by KBTBD13-low versus KBTBD13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD13→partner) and Y-score (partner→KBTBD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTSPY25P →+0.094+8.066<.001.00731
STADMIR551A →+0.623+4.184<.001.00931
STADMIR4667 →+0.423+4.440<.001.00631
SKCMLINC00604 →+0.167+3.766<.001.00531
SKCMRNU6-107P →+0.325+3.287.006.00831
SKCMMTND2P38 →+0.037+4.362<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

TSPY25P by KBTBD13 expression — UCEC

Box plot of TSPY25P in KBTBD13-low vs KBTBD13-high samples in UCEC.

Explore this box plot interactively →

Exploration