KBTBD13

Across TCGA pan-cancer cohorts, KBTBD13 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated KBTBD13 data layer compared with 2 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher KBTBD13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KBTBD13 expression acts as an unfavorable survival marker, although some lineages such as SCLC and CESC show a favorable association.

DLBC, ACC, and KIRP are the cancer types where KBTBD13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	II,III,IV	0.124	0.884	<.001	108	view →
ACC	DFS	Tertile	III,IV	0.046	0.670	.001	63	view →
KIRP	DFS	Quartile	IV	0.033	0.526	.001	58	view →
SCLC	DFS	Median	All	0.715	0.399	<.001	49	view →
COAD	OS	Tertile	IV	0.185	0.612	.005	39	view →
LIHC	DFS	Tertile	All	0.307	0.592	<.001	36	view →
LUAD	DFS	Tertile	IV	0.389	0.803	.002	36	view →
THYM	OS	Tertile	II,III,IV	0.811	0.975	.002	27	view →
CESC	OS	Tertile	All	0.942	0.848	.015	24	view →
MESO	DFS	Tertile	III,IV	0.116	0.492	.010	18	view →
THCA	OS	Quartile	III,IV	0.903	0.986	.003	17	view →
SKCM	OS	Tertile	All	0.194	0.335	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

KBTBD13–DLBC (DFS)

Open the DLBC breakdown →