KATNB1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KATNB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,119 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KATNB1-associated GO terms across cancer lineages are Chromosome movement towards spindle pole, Mitotic chromosome movement towards spindle pole, and Microtubule depolymerization. Each is linked with KATNB1 in more than 17 cancer types. Because this analysis shows association rather than direction, both KATNB1-to-partner and partner-to-KATNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome movement towards spindle pole grouped by KATNB1-low versus KATNB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNB1→partner) and Y-score (partner→KATNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEChromosome movement towards spindle pole →+0.179+1.259.001.002318
BREASTMitotic chromosome movement towards spindle pole →+0.148+0.978<.001<.001318
BONEMicrotubule depolymerization →+0.175+1.040<.001<.001316
BONERibosomal large subunit assembly →+0.112+0.748.005.006314
URINARY_TRACTProtein depolymerization →+0.150+1.115<.001.001314
URINARY_TRACTIMP biosynthetic process →+0.226+1.258<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,119 associations by consensus.

Chromosome movement towards spindle pole by KATNB1 expression — BONE

Box plot of Chromosome movement towards spindle pole in KATNB1-low vs KATNB1-high samples in BONE.

Explore this box plot interactively →

Exploration