JUNB

Across TCGA cell cohorts, JUNB mutation is significantly associated with the mutation status of many other genes, with 1,861 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JUNB-associated genes across cancer lineages are USP54, ZBTB37, and WT1. Each is linked with JUNB in more than 2 cancer types. Because this analysis shows association rather than direction, both JUNB-to-partner and partner-to-JUNB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP54 grouped by JUNB-low versus JUNB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUNB→partner) and Y-score (partner→JUNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	USP54 →	+3.145	+3.932	.004	.004	1	3
BREAST	ZBTB37 →	+4.857	+4.297	.009	.009	1	3
LUNG_NSCLC_LUAD	WT1 →	+4.339	+4.339	.009	.009	1	3
LARGE_INTESTINE	FZD3 →	+4.799	+3.672	.002	.002	1	3
LARGE_INTESTINE	NOTCH2 →	+1.951	+3.015	.006	.006	1	3
LUNG_NSCLC_LUAD	FXR1 →	+4.339	+4.339	.009	.009	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,861 associations by consensus.

USP54 by JUNB expression — BLOOD_Leukemia

Explore this box plot interactively →