JUNB

Across TCGA pan-cancer cohorts, JUNB RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of JUNB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where JUNB RNA is repressed in tumor relative to normal tissue. In most cancer types JUNB is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and BLCA are the cancer types where JUNB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JUNB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.824	<.001	11	view →
KIRP	Female	All	−1.608	<.001	7	view →
BLCA	All	All	−1.293	<.001	7	view →
UCEC	All	II,III,IV	−3.100	<.001	6	view →
LUAD	Female	All	−1.017	<.001	6	view →
BRCA	All	II,III,IV	−0.828	<.001	6	view →
LIHC	Male	All	−1.083	<.001	5	view →
LUSC	All	All	−0.904	<.001	5	view →
THCA	All	All	−0.557	.003	3	view →
COAD	All	All	+0.358	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

JUNB–KICH

Open the KICH breakdown →