JSRP1

Across TCGA patient cohorts, JSRP1 mutation is significantly associated with the RNA expression of many other genes, with 129 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JSRP1-associated genes across cancer lineages are RNU5E-9P, LINC02508, and MIR3661. Each is linked with JSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JSRP1-to-partner and partner-to-JSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by JSRP1-low versus JSRP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JSRP1→partner) and Y-score (partner→JSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-9P →	+0.280	+4.470	<.001	.004	3	2
BLCA	LINC02508 →	+0.106	+4.899	<.001	.005	3	2
SKCM	MIR3661 →	+0.298	+3.623	<.001	.006	3	2
BRCA	DUX4L28 →	+0.074	+9.057	<.001	.003	3	1
UCEC	CTHRC1P1 →	+0.141	+4.109	<.001	<.001	3	1
BRCA	MTCO3P30 →	+0.074	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

RNU5E-9P by JSRP1 expression — UCEC

Explore this box plot interactively →