Across TCGA pan-cancer cohorts, JSRP1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of JSRP1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where JSRP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types JSRP1 is over-expressed in tumor.
LUAD, COAD, and KIRC are the cancer types where JSRP1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JSRP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.