JRK

Across TCGA patient cohorts, JRK RNA expression is significantly associated with the protein abundance of many other proteins, with 16,807 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JRK-associated proteins across cancer lineages are WDR5, SMC1A, and SMC3. Each is linked with JRK in more than 6 cancer types. Because this analysis shows association rather than direction, both JRK-to-partner and partner-to-JRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JRK versus WDR5 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JRK→partner) and Y-score (partner→JRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR5 →	+0.301	+0.348	<.001	<.001	3	7
GBM	SMC1A →	+0.395	+0.498	<.001	<.001	3	7
GBM	SMC3 →	+0.287	+0.287	<.001	<.001	3	7
GBM	RAD21 →	+0.277	+0.324	<.001	<.001	3	6
GBM	SIN3A →	+0.271	+0.396	<.001	<.001	3	6
GBM	DHX9 →	+0.236	+0.313	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,807 associations by consensus.

JRK vs WDR5 — GBM

Explore this scatter interactively →