JRK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JRK protein abundance is significantly associated with the RNA expression of many other genes, with 1,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JRK-associated genes across cancer lineages are RPS20P24, TSNARE1, and LY6G5B. Each is linked with JRK in more than 1 cancer types. Because this analysis shows association rather than direction, both JRK-to-partner and partner-to-JRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JRK versus RPS20P24 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JRK→partner) and Y-score (partner→JRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRPS20P24 →+2.667+0.739.008.00232
LSCCTSNARE1 →+0.742+0.634.002.00432
BRCALY6G5B →+0.536+0.639<.001.00232
OVZNF426-DT →+0.946+0.496.005.00332
OVTARDBPP2 →+1.186+0.644<.001.00232
LUADFSCN3 →+0.223+0.297.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,359 associations by consensus.

JRK vs RPS20P24 — OV

Per-sample scatter of JRK vs RPS20P24 in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration