JMJD7-PLA2G4B

Across TCGA patient cohorts, JMJD7-PLA2G4B mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JMJD7-PLA2G4B-associated genes across cancer lineages are ATM, MSH6, and STAT3_pY705. Each is linked with JMJD7-PLA2G4B in more than 2 cancer types. Because this analysis shows association rather than direction, both JMJD7-PLA2G4B-to-partner and partner-to-JMJD7-PLA2G4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by JMJD7-PLA2G4B-low versus JMJD7-PLA2G4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD7-PLA2G4B→partner) and Y-score (partner→JMJD7-PLA2G4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.558	-2.459	<.001	<.001	3	3
UCEC	MSH6 →	-0.346	-2.584	.002	.010	3	2
UCEC	STAT3_pY705 →	-0.340	-1.492	<.001	.027	3	2
UCEC	TFRC →	+0.595	+3.700	.001	.001	3	2
UCEC	DJ-1 →	+0.144	+2.807	.012	.003	3	2
UCEC	14-3-3_beta →	-0.082	-1.847	.018	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

ATM by JMJD7-PLA2G4B expression — UCEC

Explore this box plot interactively →