JMJD7-PLA2G4B

Across TCGA pan-cancer cohorts, JMJD7-PLA2G4B RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of JMJD7-PLA2G4B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where JMJD7-PLA2G4B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types JMJD7-PLA2G4B is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

COAD, BRCA, and CHOL are the cancer types where JMJD7-PLA2G4B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JMJD7-PLA2G4B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.488	<.001	8	view →
BRCA	Female	All	−0.619	<.001	6	view →
CHOL	All	All	+1.077	.001	5	view →
READ	All	All	+0.600	.002	5	view →
LIHC	All	All	+0.222	<.001	5	view →
LUAD	All	All	−0.330	.005	4	view →
KIRC	All	All	+0.199	.001	4	view →
LUSC	Male	All	+0.421	.024	2	view →
THCA	All	All	−0.324	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

JMJD7-PLA2G4B–COAD

Open the COAD breakdown →