JAZF1

Across TCGA patient cohorts, JAZF1 mutation is significantly associated with the RNA expression of many other genes, with 3,895 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JAZF1-associated genes across cancer lineages are RN7SL248P, RN7SL478P, and RNU6-525P. Each is linked with JAZF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both JAZF1-to-partner and partner-to-JAZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by JAZF1-low versus JAZF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAZF1→partner) and Y-score (partner→JAZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.053	+2.985	<.001	.006	3	3
UCEC	RN7SL478P →	+0.180	+1.716	.002	.006	3	2
LUSC	RNU6-525P →	+0.537	+5.211	<.001	.007	3	2
UCEC	ATP6V1G1P4 →	+0.348	+1.910	<.001	.001	3	2
UCEC	BNIP3P41 →	+0.010	+4.086	<.001	.005	3	2
UCEC	RNA5SP423 →	+0.591	+1.810	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,895 associations by consensus.

RN7SL248P by JAZF1 expression — UCEC

Explore this box plot interactively →