ITGB6

Across TCGA patient cohorts, ITGB6 protein abundance is significantly associated with the RNA expression of many other genes, with 14,861 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITGB6-associated genes across cancer lineages are ITGAV, PLAU, and PMEPA1. Each is linked with ITGB6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITGB6-to-partner and partner-to-ITGB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB6 versus ITGAV in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB6→partner) and Y-score (partner→ITGB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGAV →	+0.914	+0.785	<.001	.001	3	6
BRCA	PLAU →	+1.306	+0.975	<.001	<.001	3	5
LSCC	PMEPA1 →	+1.361	+0.940	<.001	<.001	3	5
LSCC	LOXL2 →	+0.889	+0.709	<.001	<.001	3	5
HNSC	C10orf55 →	+0.359	+0.824	.004	.001	3	5
OV	RPARP-AS1 →	-0.723	-1.046	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,861 associations by consensus.

ITGB6 vs ITGAV — OV

Explore this scatter interactively →