ITGB3BP

Across TCGA patient cohorts, ITGB3BP protein abundance is significantly associated with the RNA expression of many other genes, with 512 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ITGB3BP-associated genes across cancer lineages are MTIF3, RWDD3, and SLC25A35. Each is linked with ITGB3BP in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGB3BP-to-partner and partner-to-ITGB3BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITGB3BP versus MTIF3 in BRCA, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB3BP→partner) and Y-score (partner→ITGB3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MTIF3 →	-0.585	-0.545	.002	.008	3	1
BRCA	RWDD3 →	-0.592	-0.564	.001	.006	3	1
BRCA	SLC25A35 →	-1.110	-0.738	.008	.009	3	1
BRCA	TPT1 →	-0.740	-0.545	.002	.008	3	1
BRCA	HRK →	+0.895	+0.575	.001	.005	3	1
BRCA	RNFT2 →	+0.703	+0.592	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 512 associations by consensus.

ITGB3BP vs MTIF3 — BRCA

Explore this scatter interactively →