ITGB1BP1

Across TCGA patient cohorts, ITGB1BP1 mutation is significantly associated with the RNA expression of many other genes, with 700 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITGB1BP1-associated genes across cancer lineages are RN7SL248P, POMPP1, and MIR4752. Each is linked with ITGB1BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGB1BP1-to-partner and partner-to-ITGB1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ITGB1BP1-low versus ITGB1BP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGB1BP1→partner) and Y-score (partner→ITGB1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.105	+4.137	<.001	<.001	3	2
UCEC	POMPP1 →	+0.142	+3.036	<.001	.009	3	2
UCEC	MIR4752 →	+0.187	+5.744	<.001	<.001	3	2
SKCM	MIR6882 →	+0.547	+5.680	<.001	.003	3	1
COAD	OR4C46 →	+0.179	+7.741	<.001	.009	3	1
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 700 associations by consensus.

RN7SL248P by ITGB1BP1 expression — UCEC

Explore this box plot interactively →