ITGA7

Across TCGA cell cohorts, ITGA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,271 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ITGA7-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Cytoplasmic translation, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ITGA7 in more than 13 cancer types. Because this analysis shows association rather than direction, both ITGA7-to-partner and partner-to-ITGA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ITGA7-low versus ITGA7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA7→partner) and Y-score (partner→ITGA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.145	+1.189	<.001	<.001	3	14
OESOPHAGUS	Cytoplasmic translation →	+0.127	+1.341	<.001	.002	3	14
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.121	+1.110	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translational initiation →	+0.085	+0.949	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Ribonucleoside triphosphate biosynthetic process →	+0.098	+0.880	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Translational initiation →	+0.082	+0.832	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,271 associations by consensus.

Negative regulation of myoblast fusion by ITGA7 expression — OESOPHAGUS

Explore this box plot interactively →