ITGA7

Across TCGA pan-cancer cohorts, ITGA7 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ITGA7 data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ITGA7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ITGA7 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SARC show a favorable association.

BLCA, UVM, and ACC are the cancer types where ITGA7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.343	0.515	<.001	100	view →
UVM	DFS	Tertile	II,III,IV	0.376	0.736	<.001	89	view →
ACC	DFS	Median	All	0.173	0.680	<.001	81	view →
LGG	OS	Median	All	0.343	0.518	<.001	54	view →
COAD	DFS	Quartile	All	0.738	0.869	.001	48	view →
PAAD	OS	Tertile	All	0.518	0.297	.003	44	view →
SARC	OS	Tertile	All	0.837	0.616	<.001	37	view →
LAML	DFS	Tertile	All	0.396	0.808	<.001	36	view →
UCEC	OS	Median	All	0.573	0.773	<.001	30	view →
UCS	OS	Tertile	III,IV	0.662	0.345	.018	24	view →
THCA	DFS	Quartile	IV	0.959	0.629	.004	19	view →
LUSC	DFS	Median	II,III,IV	0.654	0.778	.016	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ITGA7–BLCA (OS)

Open the BLCA breakdown →