ITGA7

Across TCGA pan-cancer cohorts, ITGA7 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ITGA7’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ITGA7 RNA is repressed in tumor relative to normal tissue. In most cancer types ITGA7 is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.

BLCA, LIHC, and KIRC are the cancer types where ITGA7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ITGA7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	IV	−4.342	<.001	11	view →
LIHC	All	III,IV	+1.464	<.001	9	view →
KIRC	Female	All	+1.084	<.001	8	view →
LUSC	All	II,III,IV	−0.887	<.001	7	view →
BRCA	All	III,IV	−3.202	<.001	6	view →
UCEC	All	III,IV	−3.187	<.001	6	view →
COAD	All	II,III,IV	−1.053	<.001	6	view →
THCA	All	All	+0.770	<.001	5	view →
READ	All	All	−1.752	.005	4	view →
LUAD	Male	All	−0.427	.019	4	view →
PRAD	All	All	−0.812	<.001	2	view →
HNSC	Male	IV	−1.590	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ITGA7–BLCA

Open the BLCA breakdown →