ITGA10

Across TCGA cell cohorts, ITGA10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ITGA10-associated GO terms across cancer lineages are Negative regulation of organelle assembly, Regulation of cilium assembly, and Proteoglycan biosynthetic process. Each is linked with ITGA10 in more than 7 cancer types. Because this analysis shows association rather than direction, both ITGA10-to-partner and partner-to-ITGA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of organelle assembly grouped by ITGA10-low versus ITGA10-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA10→partner) and Y-score (partner→ITGA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of organelle assembly →	+0.042	+0.344	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of cilium assembly →	+0.055	+0.494	<.001	<.001	3	7
BONE	Proteoglycan biosynthetic process →	+0.092	+1.631	<.001	<.001	3	7
LARGE_INTESTINE	Intraciliary anterograde transport →	+0.068	+0.329	<.001	<.001	3	7
LARGE_INTESTINE	Negative regulation of G1/S transition of mitotic cell cycle →	+0.100	+0.495	<.001	<.001	3	7
URINARY_TRACT	Positive regulation of cilium assembly →	+0.094	+0.491	.003	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Negative regulation of organelle assembly by ITGA10 expression — BLOOD_Leukemia

Explore this box plot interactively →