ITGA10

Across TCGA cell cohorts, ITGA10 mutation is significantly associated with the RNA expression of many other genes, with 1,115 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITGA10-associated genes across cancer lineages are TBL1X, HDDC2, and NQO2. Each is linked with ITGA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITGA10-to-partner and partner-to-ITGA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBL1X grouped by ITGA10-low versus ITGA10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITGA10→partner) and Y-score (partner→ITGA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBL1X →	+0.933	+2.158	.007	.004	3	2
LARGE_INTESTINE	HDDC2 →	+0.558	+2.158	.005	.004	3	2
LARGE_INTESTINE	NQO2 →	+0.859	+2.158	.002	.004	3	2
LARGE_INTESTINE	CARD6 →	-0.604	-2.072	.008	.008	3	2
LARGE_INTESTINE	CNNM2 →	+0.545	+3.082	.003	.007	3	2
LARGE_INTESTINE	FYCO1 →	+0.532	+2.850	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,115 associations by consensus.

TBL1X by ITGA10 expression — LARGE_INTESTINE

Explore this box plot interactively →