ISCUP1

Across TCGA patient cohorts, ISCUP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,447 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ISCUP1-associated GO terms across cancer lineages are Sterol transport, Hindbrain development, and Positive regulation of ubiquitin-dependent protein catabolic process. Each is linked with ISCUP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ISCUP1-to-partner and partner-to-ISCUP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sterol transport grouped by ISCUP1-low versus ISCUP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ISCUP1→partner) and Y-score (partner→ISCUP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Sterol transport →	+0.084	+0.044	<.001	<.001	3	7
STAD	Hindbrain development →	+0.072	+0.050	<.001	<.001	3	7
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.126	+0.052	<.001	<.001	3	7
STAD	Pyridine-containing compound metabolic process →	+0.095	+0.060	<.001	<.001	3	7
STAD	Negative regulation of cytoskeleton organization →	+0.096	+0.048	<.001	<.001	3	6
STAD	Maintenance of location in cell →	+0.099	+0.055	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,447 associations by consensus.

Sterol transport by ISCUP1 expression — STAD

Explore this box plot interactively →