ISCA1

Across TCGA patient cohorts, ISCA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,657 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ISCA1-associated proteins across cancer lineages are RAD23B, CASP4, and RABL6. Each is linked with ISCA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ISCA1-to-partner and partner-to-ISCA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ISCA1 versus RAD23B in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ISCA1→partner) and Y-score (partner→ISCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAD23B →	+0.259	+0.496	<.001	<.001	3	6
GBM	CASP4 →	-0.613	-0.314	<.001	.003	3	5
OV	RABL6 →	+0.300	+0.430	.003	.003	3	5
BRCA	C9orf64 →	+0.320	+0.403	.001	.002	3	5
OV	ECPAS →	+0.353	+0.666	.001	<.001	3	5
PDAC	FAM120A →	+0.176	+0.337	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,657 associations by consensus.

ISCA1 vs RAD23B — BRCA

Explore this scatter interactively →