IRX5

Across TCGA patient cohorts, IRX5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,746 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IRX5-associated genes across cancer lineages are ABCD3, SELENBP1, and MOAP1. Each is linked with IRX5 in more than 2 cancer types. Because this analysis shows association rather than direction, both IRX5-to-partner and partner-to-IRX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRX5 versus ABCD3 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX5→partner) and Y-score (partner→IRX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ABCD3 →	+0.812	+0.582	<.001	<.001	3	3
BRCA	SELENBP1 →	+1.418	+0.519	<.001	.001	3	3
BRCA	MOAP1 →	+0.654	+0.458	<.001	.003	3	3
LUAD	IRX3 →	+0.857	+0.654	<.001	<.001	3	3
BRCA	ACADSB →	+1.460	+0.768	<.001	<.001	3	3
LUAD	CRNDE →	+0.804	+0.819	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,746 associations by consensus.

IRX5 vs ABCD3 — BRCA

Explore this scatter interactively →