IRX4-AS1

Across TCGA patient cohorts, IRX4-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,761 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible IRX4-AS1-associated GO terms across cancer lineages are Pancreatic A cell differentiation, Proximal/distal pattern formation, and Negative regulation of epidermis development. Each is linked with IRX4-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IRX4-AS1-to-partner and partner-to-IRX4-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pancreatic A cell differentiation grouped by IRX4-AS1-low versus IRX4-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX4-AS1→partner) and Y-score (partner→IRX4-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Pancreatic A cell differentiation →	-0.116	-1.121	<.001	<.001	3	8
ESCA	Proximal/distal pattern formation →	+0.073	+1.447	<.001	<.001	3	8
ESCA	Negative regulation of epidermis development →	+0.052	+0.917	<.001	.002	3	8
ESCA	Inner ear receptor cell fate commitment →	+0.118	+1.494	<.001	<.001	3	8
ESCA	Regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation →	-0.089	-1.463	<.001	<.001	3	7
ESCA	Metanephric glomerulus development →	-0.085	-1.125	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,761 associations by consensus.

Pancreatic A cell differentiation by IRX4-AS1 expression — ESCA

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