IRF2-DT

Across TCGA patient cohorts, IRF2-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,711 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IRF2-DT-associated proteins across cancer lineages are THYN1, PSMB5, and PSMB6. Each is linked with IRF2-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both IRF2-DT-to-partner and partner-to-IRF2-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2-DT versus THYN1 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2-DT→partner) and Y-score (partner→IRF2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THYN1 →	+0.348	+0.455	<.001	<.001	3	4
HNSC	PSMB5 →	-0.402	-0.482	<.001	.002	3	4
HNSC	PSMB6 →	-0.352	-0.480	.001	<.001	2	5
OV	CDKN2AIP →	+0.358	+0.662	<.001	<.001	3	4
CCRCC	RASAL3_S831 →	+0.467	+0.344	.002	<.001	3	3
OV	IRF2 →	+0.291	+0.468	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,711 associations by consensus.

IRF2-DT vs THYN1 — HNSC

Explore this scatter interactively →