Across TCGA patient cohorts, IQCF6 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IQCF6-associated genes across cancer lineages are RNU6-1146P, FAM27B, and RPSAP57. Each is linked with IQCF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCF6-to-partner and partner-to-IQCF6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF6→partner) and Y-score (partner→IQCF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1146P →	+0.312	+7.741	.003	.009	3	1
UCEC	FAM27B →	+0.164	+4.868	<.001	.004	3	1
UCEC	RPSAP57 →	+0.105	+3.809	<.001	.007	3	1
UCEC	IGHV1OR15-4 →	+0.211	+4.352	<.001	.008	3	1
UCEC	FSCB →	+0.063	+4.026	.006	.006	3	1
UCEC	MIR342 →	+0.602	+3.831	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

IQCF6 survival (RNA) · tumor vs normal (RNA) · all IQCF6 data types