Across TCGA cell cohorts, INSYN2A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INSYN2A-associated genes across cancer lineages are OR14A16, KRTAP9-1, and OR5M10. Each is linked with INSYN2A in more than 1 cancer types. Because this analysis shows association rather than direction, both INSYN2A-to-partner and partner-to-INSYN2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2A→partner) and Y-score (partner→INSYN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR14A16 →	+0.013	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP9-1 →	+0.032	+4.662	<.001	.003	3	1
BLOOD_Lymphoma	OR5M10 →	+0.011	+4.058	<.001	.009	3	1
OVARY	MROH2B →	+0.061	+5.339	<.001	<.001	3	1
BLOOD_Leukemia	SCGB1C1 →	+0.140	+5.539	<.001	.003	3	1
BLOOD_Leukemia	RDH8 →	+0.021	+5.201	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

INSYN2A survival (RNA) · tumor vs normal (RNA) · all INSYN2A data types