INPP5K

Across TCGA patient cohorts, INPP5K protein abundance is significantly associated with the RNA expression of many other genes, with 5,215 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INPP5K-associated genes across cancer lineages are ACAP1, SLC2A1, and CLEC9A. Each is linked with INPP5K in more than 3 cancer types. Because this analysis shows association rather than direction, both INPP5K-to-partner and partner-to-INPP5K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP5K versus ACAP1 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5K→partner) and Y-score (partner→INPP5K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACAP1 →	+0.554	+0.171	.003	.007	3	4
LSCC	SLC2A1 →	-1.393	-0.207	<.001	<.001	3	4
CCRCC	CLEC9A →	+0.600	+0.184	<.001	.003	3	4
LSCC	MYO1C →	+0.485	+0.217	.001	<.001	3	4
COAD	RABEP1 →	+0.518	+0.256	<.001	.004	3	4
HNSC	PAFAH1B1 →	+0.478	+0.242	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,215 associations by consensus.

INPP5K vs ACAP1 — UCEC

Explore this scatter interactively →