Across TCGA patient cohorts, INPP5J protein abundance is significantly associated with the RNA expression of many other genes, with 5,432 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible INPP5J-associated genes across cancer lineages are CYP4X1, CAB39L, and ATP1B1. Each is linked with INPP5J in more than 2 cancer types. Because this analysis shows association rather than direction, both INPP5J-to-partner and partner-to-INPP5J results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5J→partner) and Y-score (partner→INPP5J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CYP4X1 →	+2.675	+0.952	<.001	<.001	3	3
BRCA	CAB39L →	+0.538	+0.600	.004	<.001	3	3
BRCA	ATP1B1 →	+0.740	+0.638	.009	.001	3	3
GBM	SEC14L5 →	+1.051	+0.500	<.001	<.001	3	2
LUAD	AQP9 →	-0.835	-0.524	.004	.006	3	2
LUAD	IKBKB →	+0.687	+0.676	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,432 associations by consensus.

Exploration

INPP5J survival (RNA) · tumor vs normal (RNA) · all INPP5J data types