INO80C

Across TCGA patient cohorts, INO80C protein abundance is significantly associated with the RNA expression of many other genes, with 4,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INO80C-associated genes across cancer lineages are PBK, LIMCH1, and PRMT2. Each is linked with INO80C in more than 2 cancer types. Because this analysis shows association rather than direction, both INO80C-to-partner and partner-to-INO80C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INO80C versus PBK in LUAD, with a Pearson correlation of 0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80C→partner) and Y-score (partner→INO80C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PBK →	+0.843	+0.165	.005	.004	3	3
BRCA	LIMCH1 →	-0.943	-0.201	.001	.001	3	3
PDAC	PRMT2 →	-0.365	-0.311	<.001	.003	3	3
LSCC	GLIS3 →	-0.550	-0.161	<.001	<.001	3	3
BRCA	KIFC1 →	+0.685	+0.199	.004	.001	3	3
PDAC	MSNP1 →	-0.382	-0.389	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,704 associations by consensus.

INO80C vs PBK — LUAD

Explore this scatter interactively →