INO80C

Across TCGA pan-cancer cohorts, INO80C RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of INO80C’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where INO80C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types INO80C is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where INO80C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INO80C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+1.252	<.001	12	view →
KICH	All	III,IV	−1.188	<.001	10	view →
LIHC	Male	II,III,IV	+0.839	<.001	9	view →
BLCA	All	III,IV	+0.853	.006	8	view →
LUAD	All	II,III,IV	−0.397	<.001	8	view →
COAD	All	IV	−0.580	.018	5	view →
CHOL	Male	All	+1.740	<.001	3	view →
READ	Female	All	−0.532	.008	2	view →
THCA	Male	All	+0.303	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

INO80C–KIRC

Open the KIRC breakdown →